Schofield C, Ashworth A
Centre for Human Nutrition, London School of Hygiene and Tropical Medicine, England.
Bull World Health Organ. 1996;74(2):223-9.
A review of the literature that has appeared over the past five decades indicates that the median case fatality from severe malnutrition has remained unchanged over this period and is typically 20-30%, with the highest levels (50-60%) being among those with oedematous malnutrition. A likely cause of this continuing high mortality is faulty case-management. A survey of treatment centres worldwide (n = 79) showed that for acutely ill children, inappropriate diets that are high in protein, energy and sodium and low in micronutrients are commonplace. Practices that could have fatal consequences, such as prescribing diuretics for oedema, were found to be widespread. Evidence of outmoded and conflicting teaching manuals also emerged. Since low mortality levels from malnutrition can be achieved using appropriate treatment regimens, updated treatment guidelines, which are practical and prescriptive rather than descriptive, need to be implemented as part of a comprehensive training programme.
对过去五十年来发表的文献进行回顾表明,在此期间,严重营养不良的病例死亡率中位数保持不变,通常为20%-30%,其中水肿型营养不良患者的死亡率最高(50%-60%)。持续高死亡率的一个可能原因是病例管理不当。一项对全球治疗中心(n = 79)的调查显示,对于急性病患儿,蛋白质、能量和钠含量高而微量营养素含量低的不适当饮食很常见。发现一些可能导致致命后果的做法,如为水肿患者开利尿剂,很普遍。还出现了过时且相互矛盾的教学手册的证据。由于采用适当的治疗方案可以实现低营养不良死亡率,因此需要实施实用且具有规范性而非描述性的更新治疗指南,并将其作为全面培训计划的一部分。