Kurth K H, Altwein J E, Skoluda D, Hohenfellner R
J Urol. 1977 May;117(5):615-7. doi: 10.1016/s0022-5347(17)58555-9.
Of 66 patients with irradiated prostatic carcinoma 53 were controlled regularly by repeat aspiration biopsy every 6 months. Local sterilization was achieved in 43 per cent but the results of combined radiotherapy (endocrine therapy plus irradiation) were only 8 per cent more favorable than those in patients treated by radiotherapy alone. Thus, endocrine therapy is not warranted before the radiation effect is evaluated. Post-radiation treatment should be determined by the clinical and bioptic findings.
在66例接受过放射治疗的前列腺癌患者中,53例每6个月通过重复穿刺活检进行定期监测。43%的患者实现了局部肿瘤消除,但联合放疗(内分泌治疗加放疗)的效果仅比单纯放疗患者高8%。因此,在评估放疗效果之前,内分泌治疗并无必要。放疗后的治疗应根据临床和活检结果来确定。