Dietze G, Wicklmayr M
Klin Wochenschr. 1977 Apr 1;55(7):357-8. doi: 10.1007/BF01488118.
Glucose metabolism of the human forearm was studied in 4 healthy volunteers by monitoring arterial deepvenous glucose concentration differences and by the determination of muscle blood flow, using 133xenon as a tracer, during 25 min intra-brachial-arterial infusion of bradykinin (13.3 ng per min). During the infusion of the kinine the forearms glucose uptake rose continuously from 0.64 +/- 0.11 micronmoles up to 1.68 +/- 0.22 micronmoles per 100 g x min after 25 min of the infusion (p less than 0.005). The enhancement of glucose uptake was partly due to the prompt small acceleration of muscle blood flow and partly to the continuously increasing glucose extraction of the forearm. From these data it is evident that besides insulin there is another physiological agent able to enhance glucose entry into the muscle cell.
通过监测动脉-深静脉葡萄糖浓度差异，并在使用133氙作为示踪剂测定肌肉血流量的情况下，对4名健康志愿者的人前臂葡萄糖代谢进行了研究。在肱动脉内输注缓激肽（每分钟13.3纳克）25分钟期间进行上述操作。在输注激肽期间，前臂葡萄糖摄取量从每100克×分钟0.64±0.11微摩尔持续上升至输注25分钟后的1.68±0.22微摩尔（p<0.005）。葡萄糖摄取增强部分归因于肌肉血流量迅速小幅加速，部分归因于前臂葡萄糖提取持续增加。从这些数据可以明显看出，除胰岛素外，还有另一种生理因子能够增强葡萄糖进入肌肉细胞。
