治疗相关的髓系白血病
Therapy-related myeloid leukemia.
作者信息
Thirman M J, Larson R A
机构信息
Section of Hematology/Oncology, Pritzker School of Medicine, University of Chicago, Illinois, USA.
出版信息
Hematol Oncol Clin North Am. 1996 Apr;10(2):293-320. doi: 10.1016/s0889-8588(05)70340-3.
One of the most serious possible consequences of cancer therapy is the development of a second cancer, especially leukemia. Several distinct subsets of therapy-related leukemia can be distinguished currently. These include classic therapy-related myeloid leukemia, leukemia that follows treatment with agents that inhibit topoisomerase II, acute lymphoblastic leukemia, and leukemias with 21q22 rearrangements or inv(16) or t(15;17). These types of leukemia are discussed in detail in this article.
癌症治疗最严重的潜在后果之一是引发第二种癌症，尤其是白血病。目前可以区分出几种不同类型的治疗相关白血病。这些包括经典的治疗相关髓系白血病、使用拓扑异构酶II抑制剂治疗后发生的白血病、急性淋巴细胞白血病，以及伴有21q22重排、inv(16)或t(15;17)的白血病。本文将详细讨论这些类型的白血病。
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