Popovichenko N V, Chebotareva L L, Pivnenko G M, Pelevin Iu M
Neirofiziologiia. 1977;9(2):157-64.
Bilateral electrolytic destruction of the paramedian midbrain caudal tegmentum caused the appearance in the internal part of the hypothalamic supraoptic nucleus of neurosecretory cells with low functional activity and degenerating forms (dark-stained and pycnomorphic cells); in the posterior hypophysis the destructed gigantic terminal varicosities (Herring bodies) were revealed; the posterior hypophysis contained a subnormal amount of neurosecret; the vasopressin-antidiuretic hormone level in blood plasma was reduced. Painful stimulation of animals with the destructed midbrain tegmentum revealed the functional insufficiency of the supraoptic hypophyseal neurosecretory system (SHNS). The results obtained permit considering that the paramedian midbrain tegmentum exerts a modulating influence upon the SHNS function during stress.
双侧电解损毁中脑被盖尾部的旁正中区域，导致下丘脑视上核内部出现功能活性低且有退化形态（深色染色和致密形态细胞）的神经分泌细胞；在垂体后叶发现了被损毁的巨大终末膨体（赫林体）；垂体后叶所含神经分泌物质数量低于正常；血浆中血管加压素 - 抗利尿激素水平降低。对中脑被盖损毁的动物进行疼痛刺激，揭示了视上垂体神经分泌系统（SHNS）的功能不足。所得结果表明，在应激期间，中脑被盖旁正中区域对SHNS功能发挥调节作用。
