维生素D代谢的现状
Current status of vitamin D metabolism.
作者信息
Fairney A
出版信息
Proc R Soc Med. 1977 Feb;70(2):89-91. doi: 10.1177/003591577707000209.
In summary one can record that the biochemist has discovered a beautiful metabolic pathway for vitamin D which is probably as yet incomplete. Subsequently the medicinal chemist has provided numerous synthetic analogues. However, delays in the diagnosis and treatment of vitamin D disorders, due to lack of specific assays and inadequate supplies of therapeutic metabolites, still unfortunately exist. It is hoped that these problems will be rectified as soon as more plentiful supplies of the appropriate metabolites are available.
综上所述，可以记录的是，生物化学家已经发现了一条关于维生素D的美妙代谢途径，而这条途径可能尚未完整。随后，药物化学家提供了众多合成类似物。然而，由于缺乏特异性检测方法以及治疗性代谢物供应不足，维生素D紊乱的诊断和治疗仍存在延误，这实在令人遗憾。希望一旦有更充足的合适代谢物供应，这些问题将尽快得到解决。
Zotero 插件