Van Ongeval J, Rutgeerts L, Ghillebert G
Sint-Vincentius Ziekenhuis, afd. Interne Geneeskunde, Belgie.
Ned Tijdschr Geneeskd. 1996 Jun 29;140(26):1367-71.
In five immunocompetent patients, 3 of whom were moderately ill, herpes simplex virus (HSV) oesophagitis was diagnosed. HSV oesophagitis is a frequent infection in immunocompromised hosts. Nevertheless the English medical literature (Medline) contains at least 33 cases of HSV oesophagitis in immunocompetent persons over the period 1983 to 1993. Odynophagia, dysphagia and chest pain are common symptoms. Endoscopy is necessary for diagnosis: brush cytology, biopsy for histology and viral culture are the tools for identification of herpes simplex as the cause of the oesophagitis. HSV oesophagitis in an immunocompetent patient is an acute but self-limiting disease. Nevertheless acyclovir per os or intravenously may be recommended if started early after onset of symptoms.
在5名免疫功能正常的患者中，其中3名病情中等，诊断为单纯疱疹病毒（HSV）食管炎。HSV食管炎在免疫功能低下的宿主中是一种常见感染。然而，英文医学文献（Medline）在1983年至1993年期间至少报道了33例免疫功能正常者患HSV食管炎的病例。吞咽痛、吞咽困难和胸痛是常见症状。诊断需要进行内镜检查：刷检细胞学、组织活检和病毒培养是确定单纯疱疹为食管炎病因的手段。免疫功能正常患者的HSV食管炎是一种急性但自限性疾病。不过，如果在症状出现后早期开始治疗，可推荐口服或静脉注射阿昔洛韦。
