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非胰岛细胞瘤所致低血糖症:一例报告并文献复习

Non-islet-cell tumour induced hypoglycaemia: a case report and review of literature.

作者信息

Kuenen B C, van Doorn J, Slee P H

机构信息

Department of Internal Medicine, St. Antonius Hospital, Nieuwegein, Netherlands.

出版信息

Neth J Med. 1996 May;48(5):175-9. doi: 10.1016/0300-2977(95)00073-9.

DOI:10.1016/0300-2977(95)00073-9
PMID:8710034
Abstract

A 54-year-old man presented with a poorly differentiated adenocarcinoma of the rectum with multiple metastases to the liver. During hospitalization the patient developed periods of hypoglycaemia due to production of "big" IGF-II by the tumour. Possible pathophysiological mechanisms of non-islet-cell tumour-induced hypoglycaemia are discussed.

摘要

一名54岁男性患者,患有直肠低分化腺癌并伴有肝脏多发转移。住院期间,该患者因肿瘤产生“大”IGF-II而出现低血糖发作。本文讨论了非胰岛细胞瘤所致低血糖的可能病理生理机制。

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Non-islet-cell tumour induced hypoglycaemia: a case report and review of literature.非胰岛细胞瘤所致低血糖症:一例报告并文献复习
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引用本文的文献

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Insulin-like growth factor-II and bioactive proteins containing a part of the E-domain of pro-insulin-like growth factor-II.胰岛素样生长因子-II 和含有胰岛素样生长因子-II E 结构域一部分的生物活性蛋白。
Biofactors. 2020 Jul;46(4):563-578. doi: 10.1002/biof.1623. Epub 2020 Feb 6.
2
Insulin-like growth factor II-producing metastatic colon cancer with recurrent hypoglycemia.产生胰岛素样生长因子II的转移性结肠癌伴复发性低血糖症。
Clin J Gastroenterol. 2015 Feb;8(1):35-40. doi: 10.1007/s12328-015-0552-4. Epub 2015 Jan 21.
3
Management of non-islet-cell tumor hypoglycemia: a clinical review.
非胰岛细胞瘤性低血糖症的管理:临床综述。
J Clin Endocrinol Metab. 2014 Mar;99(3):713-22. doi: 10.1210/jc.2013-3382. Epub 2013 Dec 11.