Kuenen B C, van Doorn J, Slee P H
Department of Internal Medicine, St. Antonius Hospital, Nieuwegein, Netherlands.
Neth J Med. 1996 May;48(5):175-9. doi: 10.1016/0300-2977(95)00073-9.
A 54-year-old man presented with a poorly differentiated adenocarcinoma of the rectum with multiple metastases to the liver. During hospitalization the patient developed periods of hypoglycaemia due to production of "big" IGF-II by the tumour. Possible pathophysiological mechanisms of non-islet-cell tumour-induced hypoglycaemia are discussed.
一名54岁男性患者,患有直肠低分化腺癌并伴有肝脏多发转移。住院期间,该患者因肿瘤产生“大”IGF-II而出现低血糖发作。本文讨论了非胰岛细胞瘤所致低血糖的可能病理生理机制。