镰状细胞病中的椎体骨质破坏：感染、梗死还是两者皆有。

Vertebral bone destruction in sickle cell disease: infection, infarction or both.

作者信息

Kooy A, de Heide L J, ten Tije A J, Mulder A H, Tanghe H L, Kluytmans J A, Michiels J J

机构信息

Department of Internal Medicine III, University Hospital Rotterdam, Netherlands.

出版信息

Neth J Med. 1996 Jun;48(6):227-31. doi: 10.1016/0300-2977(95)00075-5.

DOI:10.1016/0300-2977(95)00075-5

PMID:8710044

Abstract

Infectious and vaso-occlusive vertebral bone and joint destruction in two patients with sickle cell disease (SCD) are featured by H-shaped vertebrae, kyphotic angulation, osteolysis of endplates and collapse of intervertebral discs as shown by X-ray films and magnetic resonance imaging. Staphylococcal serology supported the diagnosis of staphylococcal osteomyelitis/spondylo-discitis in both SCD patients. The difficulties of establishing the causes and treatment of the osteoarthropathy in these particular cases are discussed in the light of the literature.

摘要

两名镰状细胞病（SCD）患者的感染性和血管阻塞性脊椎骨与关节破坏，其特征为X线片和磁共振成像所示的H形椎体、后凸成角、终板骨质溶解和椎间盘塌陷。葡萄球菌血清学支持这两名SCD患者患有葡萄球菌骨髓炎/脊椎椎间盘炎的诊断。结合文献讨论了在这些特殊病例中确定骨关节炎病因和治疗方法的困难。