Tinuper P, Avoni P, Riva R, Provini F, Lugaresi E, Baruzzi A
Department of Neurology, University of Bologna, Italy.
Neurology. 1996 Jul;47(1):76-8. doi: 10.1212/wnl.47.1.76.
We evaluated the prognostic value of the EEG in 120 seizure-free epileptic patients (49 with complex partial seizures with or without episodic secondarily generalization [CPS], 20 with simple partial seizures with or without episodic secondarily generalization [SPS], 51 with only secondarily generalized seizures [PSG] during and after antiepileptic drug withdrawal. All patients had EEG examination before; during; and 3, 12, 24, and 36 months after drug withdrawal. Relapse rates were 45% in CPS, 100% in SPS, and 65% in PSG. Before reduction, 36 patients had epileptiform EEG and 69% relapsed; in the group with normal EEG, 60% relapsed. EEG worsened in 36 patients, 83% relapsed, whereas only 54% of patients with unchanged EEG relapsed. EEG during but not at the start of drug withdrawal has a prognostic value in partial epilepsy.
我们评估了脑电图（EEG）对120例无癫痫发作的癫痫患者的预后价值，其中49例为伴有或不伴有发作性继发全面性发作的复杂部分性发作（CPS），20例为伴有或不伴有发作性继发全面性发作的简单部分性发作（SPS），51例为在停用抗癫痫药物期间及之后仅出现继发全面性发作（PSG）。所有患者在停药前、停药期间以及停药后3、12、24和36个月均进行了脑电图检查。CPS的复发率为45%，SPS为100%，PSG为65%。在脑电图改变前，36例患者脑电图有癫痫样放电，69%复发；脑电图正常组的复发率为60%。36例患者脑电图恶化，83%复发，而脑电图无变化的患者中只有54%复发。停药期间而非停药开始时的脑电图对部分性癫痫具有预后价值。
