Curio G, Drung D, Koch H, Müller W, Steinhoff U, Trahms L, Shen Y Q, Vase P, Freltoft T
Department of Neurology, Klinikum Benjamin Franklin, Freie Universität Berlin, Germany.
Neurosci Lett. 1996 Mar 15;206(2-3):204-6. doi: 10.1016/s0304-3940(96)12456-3.
Superconducting Quantum Interference Devices (SQUIDs) can be used to detect neuromagnetic fields evoked in the peripheral and central nervous system. Up to now, such measurements had to be based on SQUIDs with a low critical temperature (Tc) requiring liquid helium cooling. Recent improvements in high-Tc SQUID technology relying on liquid nitrogen cooling led to a significant reduction in the system's noise level. Hare, first high-Tc recordings of weak neuromagnetic fields are demonstrated. In particular, along the entire somatosensory afferent pathway including peripheral nerves, brachial plexus and primary somatosensory neocortex evoked neuromagnetic activities were detected using conventional recording parameters for bandwidth and number of averages. This opens up a wide perspective for cost-effective high-Tc magnetometry in clinical neuroscience.
超导量子干涉器件（SQUIDs）可用于检测外周和中枢神经系统诱发的神经磁场。到目前为止，此类测量必须基于具有低临界温度（Tc）且需要液氦冷却的SQUIDs。最近依赖液氮冷却的高温超导量子干涉器件技术的改进，使系统的噪声水平显著降低。在此，展示了对微弱神经磁场的首次高温超导量子干涉器件记录。特别是，沿着包括外周神经、臂丛神经和初级体感新皮层在内的整个体感传入通路，使用传统的带宽和平均次数记录参数检测到了诱发的神经磁活动。这为临床神经科学中具有成本效益的高温超导量子磁强计开辟了广阔前景。
