Fehér E
Acta Anat (Basel). 1977;98(1):83-90.
The structure of the nerve fibres in the chronically isolated cat ileum was studied by fluorescence and electron microscopy after 5,6-dihydroxytryptamine (5,6-DHT) treatment. Residual fluorescence rapidly disappears after administration of 5,6-DHT. Under the electron miroscope, degeneration of most of the nerve processes containing a special population of 120- to 140-nm diameter granular vesicles could be observed. Also the degeneration of presynaptic terminals in the local ganglia was observed frequently. Some degenerating nerve fibres were found in the inner muscular layer, in the connective tissue surrounding Lieberkühn's glands, and in the storma of the villi. The axons (and/or other nerve processes) undergoing degeneration are assumed to belong to the serotoninergic neurons of the local ganglia. A substantial number of nerve cell processes remaining intact after 5,6-DHT treatment contain different population of vesicles: either 30- to 60-nm agranular and 100- to 120-nm granular vesicles or 30- to 60-nm agranular and 160- to 200-nm diameter neurosecretory type vesicles.
运用荧光显微镜和电子显微镜，对经5,6 - 二羟基色胺（5,6 - DHT）处理的慢性离体猫回肠神经纤维结构进行了研究。给予5,6 - DHT后，残余荧光迅速消失。在电子显微镜下，可观察到大多数含有直径为120至140纳米特殊颗粒小泡群的神经突起发生变性。局部神经节中突触前终末的变性也经常可见。在肌内层、围绕利伯kühn腺的结缔组织以及绒毛的基质中发现了一些变性神经纤维。发生变性的轴突（和/或其他神经突起）被认为属于局部神经节的5 - 羟色胺能神经元。5,6 - DHT处理后仍保持完整的大量神经细胞突起含有不同类型的小泡：要么是30至60纳米的无颗粒小泡和100至120纳米的颗粒小泡，要么是30至60纳米的无颗粒小泡和直径为160至200纳米的神经分泌型小泡。
