Wiecek A, Kokot F
Department of Nephrology, Silesian University School of Medicine, Katowice, Poland.
Przegl Lek. 1996;53(4):356-9.
The present study aimed to assess the influence of a highly industrialized environment on the prevalence of arterial hypertension and plasma levels of cholesterol, uric acid, aldosterone and plasma renin activity. Epidemiological studies were performed in 5008 inhabitants of a highly industrialized city (Piekary Slaskie) and in 5004 inhabitants of non industrialized city (Olesno Slaskie) in the south part of Poland. Only subjects over 15 years were enrolled. The prevalence of arterial hypertension in the industrial population was 17% while in the country city 8.2%. Significantly higher serum cholesterol levels were found in hypertensive and normotensive subjects of the highly industrialized region than in the non industrialized one. Finally in hypertensive women aged < 40 years and normotensive men and women of the industrialized region significantly higher plasma renin activity and plasma aldosterone concentration were found than in corresponding population groups of the non industrialized region. From the results obtained in this study it seems, that the highly industrialized environment seems to stimulate hypertensinogenic factors.
本研究旨在评估高度工业化环境对动脉高血压患病率以及胆固醇、尿酸、醛固酮和血浆肾素活性的血浆水平的影响。对波兰南部一个高度工业化城市（皮耶卡里斯拉斯基）的5008名居民和一个非工业化城市（奥莱斯诺斯拉斯基）的5004名居民进行了流行病学研究。仅纳入15岁以上的受试者。工业人口中动脉高血压的患病率为17%，而乡村城市为8.2%。在高度工业化地区，高血压和血压正常的受试者的血清胆固醇水平显著高于非工业化地区。最后，在年龄小于40岁的高血压女性以及工业化地区血压正常的男性和女性中，发现其血浆肾素活性和血浆醛固酮浓度显著高于非工业化地区的相应人群组。从本研究获得的结果来看，高度工业化环境似乎会刺激致高血压因素。
