Fujii Y, Owada F, Higashi Y, Okuno T, Noro A
Department of Urology, Omiya Red Cross Hospital, Japan.
Hinyokika Kiyo. 1996 Feb;42(2):85-9.
In a series of 104 patients with renal cell carcinoma, a variety of clinical and histological factors were analyzed to establish their value as prognostic factors. In a univariate analysis (log-rank test), the presence or absence of symptoms, tumor size, pT, N, M, pV categories, TNM stage, Robson stage, nuclear grade and cell type were significantly associated with cause-specific survival, while age, sex and tumor side were not. In a multivariate analysis using Cox's proportional hazard model of 73 informative cases, only N (0 vs. 1-3) and M (0 vs. 1) categories of stage and nuclear grade (1-2 vs. 3) proved to be independent prognostic markers.
在一系列104例肾细胞癌患者中，分析了多种临床和组织学因素，以确定它们作为预后因素的价值。在单因素分析（对数秩检验）中，症状的有无、肿瘤大小、pT、N、M、pV分类、TNM分期、罗布森分期、核分级和细胞类型与特定病因生存率显著相关，而年龄、性别和肿瘤部位则不然。在对73例有效病例使用Cox比例风险模型进行的多因素分析中，只有N分期（0期与1 - 3期）、M分期（0期与1期）和核分级（1 - 2级与3级）被证明是独立的预后标志物。
