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[肾细胞癌的预后因素:多变量分析]

[Prognostic factors of renal cell carcinoma: a multivariate analysis].

作者信息

Fujii Y, Owada F, Higashi Y, Okuno T, Noro A

机构信息

Department of Urology, Omiya Red Cross Hospital, Japan.

出版信息

Hinyokika Kiyo. 1996 Feb;42(2):85-9.

PMID:8712093
Abstract

In a series of 104 patients with renal cell carcinoma, a variety of clinical and histological factors were analyzed to establish their value as prognostic factors. In a univariate analysis (log-rank test), the presence or absence of symptoms, tumor size, pT, N, M, pV categories, TNM stage, Robson stage, nuclear grade and cell type were significantly associated with cause-specific survival, while age, sex and tumor side were not. In a multivariate analysis using Cox's proportional hazard model of 73 informative cases, only N (0 vs. 1-3) and M (0 vs. 1) categories of stage and nuclear grade (1-2 vs. 3) proved to be independent prognostic markers.

摘要

在一系列104例肾细胞癌患者中,分析了多种临床和组织学因素,以确定它们作为预后因素的价值。在单因素分析(对数秩检验)中,症状的有无、肿瘤大小、pT、N、M、pV分类、TNM分期、罗布森分期、核分级和细胞类型与特定病因生存率显著相关,而年龄、性别和肿瘤部位则不然。在对73例有效病例使用Cox比例风险模型进行的多因素分析中,只有N分期(0期与1 - 3期)、M分期(0期与1期)和核分级(1 - 2级与3级)被证明是独立的预后标志物。

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