Jost S, Sturm M, Hausmann D, Lippolt P, Lichtlen P R
Department of Cardiology, Hannover Medical School, Germany.
Am J Cardiol. 1996 Jul 1;78(1):120-3. doi: 10.1016/s0002-9149(96)00243-3.
Maximal, reproducible, and thus "standardized" dilation of epicardial coronary arteries can be easily achieved with intracoronary bolus administration of 0.1 mg nitroglycerin without considerable decrease in blood pressure. The addition of other nitrocompounds or calcium antagonists cannot increase coronary dilation after nitroglycerin, but may be hampered by adverse effects.
通过冠状动脉内推注0.1毫克硝酸甘油,可轻松实现心外膜冠状动脉的最大程度、可重复且因此“标准化”的扩张,而血压不会显著下降。在使用硝酸甘油后,添加其他硝基化合物或钙拮抗剂并不能增加冠状动脉扩张,反而可能因不良反应而受到阻碍。