Mongiardo R, Finocchiaro M L, Beltrame J, Pristipino C, Lombardo A, Cianflone D, Mazzari M A, Maseri A
Institute of Cardiology, Catholic University of Rome, Italy.
Am J Cardiol. 1996 Jul 1;78(1):84-7. doi: 10.1016/s0002-9149(96)00230-5.
Intracoronary infusion of serotonin has been reported to induce varying degrees of coronary vasoconstriction in different coronary syndromes, but it has never been studied in patients after myocardial infarction. In patients with recent myocardial infarction, we found a low incidence (11%) of serotonin-induced occlusive spasm only in the infarct-related artery (IRA), and a significantly higher vasoconstriction in the distal segment of the IRA than in the same segment of the non-IRA.
据报道，冠状动脉内注入血清素在不同的冠状动脉综合征中可诱发不同程度的冠状动脉收缩，但从未在心肌梗死后的患者中进行过研究。在近期心肌梗死患者中，我们发现血清素诱发的闭塞性痉挛仅在梗死相关动脉（IRA）中发生率较低（11%），且IRA远端节段的血管收缩明显高于非IRA的同一节段。
