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松果体与癌症。

The pineal gland and cancer.

作者信息

Ronco A L, Halberg F

机构信息

National Cancer Registry, National Institute of Oncology, Montevideo, Uruguay.

出版信息

Anticancer Res. 1996 Jul-Aug;16(4A):2033-9.

PMID:8712739
Abstract

The pineal gland is considered today as one of the main organs involved in the transduction process which converts environmental light information into an endocrine response. The gland and its hormone melatonin seem to be important chronoimmunomodulators, and a reduction of the latter was associated with experimental and clinical immunodeficiencies and over the control of the neoplastic process. Moreover, melatonin can be an oncostatic or oncostimulating hormone, depending on the timing of its administration. The melatonin circadian rhythm is altered in cancer patients, and this rhythm could be modified as a consequence of certain therapies. Also Electromagnetic Fields (EMF) can affect the pineal function, perhaps working as synchronizers or, as this paper proposes, also through action of the "antenna effect" suggested for artificial human models, with a major energetic transfer over the cephalic area. The pineal could play an important role in the appearance and development of some forms of apparently EMF-related cancers.

摘要

如今,松果体被认为是参与转导过程的主要器官之一,该过程将环境光信息转化为内分泌反应。松果体及其激素褪黑素似乎是重要的时辰免疫调节剂,褪黑素水平的降低与实验性和临床免疫缺陷以及肿瘤进程的失控有关。此外,根据给药时间的不同,褪黑素可以是一种抑癌或促癌激素。癌症患者的褪黑素昼夜节律会发生改变,并且这种节律可能会因某些治疗而改变。电磁场(EMF)也会影响松果体功能,可能作为同步器发挥作用,或者如本文所提出的,也可能通过对人工人体模型所建议的“天线效应”起作用,在头部区域有主要的能量转移。松果体可能在某些形式的明显与电磁场相关的癌症的出现和发展中起重要作用。

相似文献

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The pineal gland and cancer.松果体与癌症。
Anticancer Res. 1996 Jul-Aug;16(4A):2033-9.
2
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Human pineal physiology and functional significance of melatonin.人类松果体生理学及褪黑素的功能意义。
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Unravelling the role of pineal gland.揭示松果体的作用。
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The human pineal gland and melatonin in aging and Alzheimer's disease.衰老与阿尔茨海默病中的人类松果体与褪黑素
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The pineal gland from development to function.松果腺的发育与功能。
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Pineal function during aging: attenuation of the melatonin rhythm and its neurobiological consequences.衰老过程中的松果体功能:褪黑素节律的衰减及其神经生物学后果。
Acta Neurobiol Exp (Wars). 1994;54 Suppl:31-9.
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Melatonin, sleep disturbance and cancer risk.褪黑素、睡眠障碍与癌症风险。
Sleep Med Rev. 2009 Aug;13(4):257-64. doi: 10.1016/j.smrv.2008.07.007. Epub 2008 Dec 17.

引用本文的文献

1
Effect of melatonin on the induction of foci of aberrant crypts in the colon by azoxymethane in rats.褪黑素对氧化偶氮甲烷诱导大鼠结肠隐窝灶形成的影响。
Environ Health Prev Med. 2004 Sep;9(5):234-7. doi: 10.1007/BF02898105.
2
Occupational and environmental agents as endocrine disruptors: experimental and human evidence.作为内分泌干扰物的职业和环境因素:实验及人体证据
J Endocrinol Invest. 2000 Dec;23(11):771-81. doi: 10.1007/BF03345069.