Imanishi K, Imachi K, Yoshito H, Isoyama T, Abe Y, Chinzei T, Mabuchi K, Kanda K, Tsutsui N, Suma K, Fujimasa I
Department of Cardiovascular Surgery, Tokyo Women's Medical College, Daini Hospital, Japan.
Artif Organs. 1996 Feb;20(2):147-51. doi: 10.1111/j.1525-1594.1996.tb00718.x.
To provide percutaneous access, a new circulatory assist system was developed. We call this newly developed system the modified assist device (MAD). The system is composed of a sac-type blood pump and cannula. Inflow and outflow valves are mounted in the apex and at the side wall 10 cm from the apex of the cannula, respectively. During systole, the blood is sucked from the left ventricle through the inflow valve of the cannula connected to the blood pump, and during diastole, the blood is ejected to the root of the aorta through the outflow valve. In vitro and in vivo evaluations of the pump performance were performed. The maximum flow rate of 1.9 L/min was obtained in the mock circulatory system. In our animal experiment, effective systolic unloading and diastolic augmentation were observed by activation of this system during regular sinus rhythm. In conclusion, the MAD-5 is thought to be percutaneously accessible and increases systemic and coronary flow.
为实现经皮接入，研发了一种新型循环辅助系统。我们将这个新研发的系统称为改良辅助装置（MAD）。该系统由一个囊式血泵和插管组成。流入阀和流出阀分别安装在插管顶端以及距插管顶端10厘米处的侧壁上。在收缩期，血液通过连接血泵的插管流入阀从左心室被吸出，在舒张期，血液通过流出阀被喷射至主动脉根部。对该泵的性能进行了体外和体内评估。在模拟循环系统中获得了1.9升/分钟的最大流速。在我们的动物实验中，在窦性心律正常时激活该系统可观察到有效的收缩期卸载和舒张期增强。总之，MAD - 5被认为可经皮接入并增加全身和冠状动脉血流。
