McDougald L R, Mathis G F, Conway D P
Georgia Poultry Research, Inc., Athens 30607, USA.
Avian Dis. 1996 Jan-Mar;40(1):68-71.
The effects of 25 ppm semduramicin, 66 ppm salinomycin, 110 ppm monensin, and unmedicated treatments on performance, shank pigmentation, and coccidial lesion scores in broiler chickens were evaluated in two floorpen trials in the United States. On day 24 of each test, birds in each treatment were inoculated via the feed with a mixture of recent field isolates of Eimeria spp. at a dose rate calculated to provide 2 x 10(5) E. acervulina, 3 x 10(4) E. maxima, and 2 x 10(4) E. tenella sporulated oocysts per bird. Weight gain and feed conversion were significantly (P < or = 0.05) improved in the semduramicin-treated broilers in comparison with the monensin-treated and unmedicated broilers. These performance variables for the salinomycin-treated birds were intermediate between the semduramicin- and monensin-treated birds. Shank pigmentation scores were significantly (P < or = 0.05) improved in the three anticoccidial treatments compared with unmedicated birds, with the highest scores (P < or = 0.05) occurring in the semduramicin-treated broilers. Semduramicin was more efficacious (P < or = 0.05) than salinomycin in controlling upper intestinal lesions and more efficacious than monensin in controlling mid-intestinal lesions. All three drugs were comparable in controlling lesions in the ceca.
在美国进行的两项地面平养试验中，评估了25 ppm的赛杜霉素、66 ppm的盐霉素、110 ppm的莫能菌素以及未用药处理对肉鸡生长性能、胫部色素沉着和球虫病变评分的影响。在每次试验的第24天，给各处理组的鸡通过饲料接种近期从田间分离的艾美耳球虫混合株，接种剂量按每只鸡提供2×10⁵个堆型艾美耳球虫、3×10⁴个巨型艾美耳球虫和2×10⁴个柔嫩艾美耳球虫的孢子化卵囊来计算。与莫能菌素处理组和未用药处理组的肉鸡相比，赛杜霉素处理组的肉鸡体重增加和饲料转化率显著提高（P≤0.05）。盐霉素处理组鸡的这些生长性能指标介于赛杜霉素处理组和莫能菌素处理组之间。与未用药的鸡相比，三种抗球虫药处理组的胫部色素沉着评分显著提高（P≤0.05），赛杜霉素处理组的肉鸡评分最高（P≤0.05）。在控制上段肠道病变方面，赛杜霉素比盐霉素更有效（P≤0.05），在控制中段肠道病变方面，赛杜霉素比莫能菌素更有效。在控制盲肠病变方面，三种药物效果相当。
