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[脉冲电流对引发机体应激反应的下丘脑神经元亚群应激限制作用的超微结构方面]

[The ultrastructural aspects of the stress-limiting action of a pulsed electrical current on the hypothalamic neuronal subpopulations that initiate the body's stress reactions].

作者信息

Bogoliubov V M, Geniatulina M S, Korolev Iu N

出版信息

Vopr Kurortol Fizioter Lech Fiz Kult. 1995 Nov-Dec(6):3-6.

PMID:8713295
Abstract

Electron-microscopic investigations of neuron subpopulations in paraventricular nuclei of rat hypothalamus demonstrated ultrastructural positive changes due to exposure of the stressed animals to impulse electric current (IEC). The latter is able to control synthesis and secretion of stress-releasing-hormones produced by neurons of hypothalamic medial small-cell and posterior large-cell subnuclei. There were indications of deposition of stress-initiating hormones in neuron bodies evidencing stress-limiting effect of IEC. There were also signs of elevated resistance of ultrastructures, endoplasmic reticulum, in particular, to stress-related damage.

摘要

对大鼠下丘脑室旁核中神经元亚群的电子显微镜研究表明,应激动物暴露于脉冲电流(IEC)后出现了超微结构的阳性变化。后者能够控制下丘脑内侧小细胞和后大细胞亚核神经元产生的应激释放激素的合成和分泌。有迹象表明应激启动激素沉积在神经元体内,证明了IEC的应激限制作用。也有超微结构,特别是内质网对应激相关损伤的抗性增强的迹象。

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