[性发育及其障碍的遗传学]
[Genetics of sexual development and its disorders].
作者信息
Osipova G R
出版信息
Genetika. 1996 Feb;32(2):184-91.
PMID:8713618
Abstract
Different hypotheses for genetic control of sexual differentiation in humans are discussed. Information on structure and manifestation of genes determining development of internal and external male genitals is considered. The process of discovering the gene responsible for differentiation of the indifferent fetal gonad into testes is described. The etiological problems of sexual development disorders are considered on the basis of knowledge obtained by modern molecular and genetic methods.
摘要
本文讨论了人类性别分化遗传控制的不同假说。考虑了决定男性内外生殖器发育的基因的结构和表现信息。描述了发现负责将胎儿未分化性腺分化为睾丸的基因的过程。基于现代分子和遗传方法获得的知识，探讨了性发育障碍的病因问题。
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