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翻修全膝关节置换术中的结构性同种异体移植

Structural allografting in revision total knee arthroplasty.

作者信息

Mow C S, Wiedel J D

机构信息

Department of Orthopaedics, University of Colorado Health Sciences Center, Denver 80262, USA.

出版信息

J Arthroplasty. 1996 Apr;11(3):235-41. doi: 10.1016/s0883-5403(96)80072-6.

Abstract

Between 1985 and 1991, 15 patients underwent structural allografting as part of revision total knee arthroplasty. All patients had large segmental, cavitary, or combination defects of the femur and/or tibia. Seven distal femurs and 12 proximal tibias required allografting. Patients were evaluated with physical examination, radiographs, and The Hospital for Special Surgery knee rating scale. Three patients died, leaving 15 allografts for follow-up study. The average age at surgery was 63 years. The follow-up period averaged 47 months (range, 30-101 months). Average range of motion before surgery was 4 degrees to 93 degrees, and after surgery, 2 degrees to 104 degrees. Average knee score was 47 before and 86 after surgery. Preoperative alignment averaged 5 degrees varus, ranging from 25 degrees valgus to 20 degrees varus, and postoperative alignment averaged 4 degrees valgus, ranging from neutral to 6 degrees valgus. All patients, except one, had improvement of pain and stability. All of the 15 allografts healed to host-bone and 13 showed evidence of incorporation. There were no infections or fractures of the allografts. One complication directly related to the allograft occurred; that patient had a tibial component fracture over a proximal tibial allograft 3 years after surgery. Three other complications occurred. One was tibial loosening in a patient who received a distal femoral allograft, the second was a proximal tibial fracture in a patient who received a distal femoral allograft, and the third was an intraoperative patellar tendon avulsion. These results suggest that structural allografting can provide a satisfactory method of managing large bone defects in the failed total knee arthroplasty.

摘要

1985年至1991年间,15例患者接受了结构性同种异体骨移植,作为全膝关节置换翻修术的一部分。所有患者均存在股骨和/或胫骨的大段、空洞性或复合型骨缺损。7例股骨远端和12例胫骨近端需要进行同种异体骨移植。通过体格检查、X线片和特殊外科医院膝关节评分量表对患者进行评估。3例患者死亡,剩余15例同种异体骨用于随访研究。手术时的平均年龄为63岁。随访期平均为47个月(范围30 - 101个月)。术前平均活动范围为4度至93度,术后为2度至104度。术前平均膝关节评分为47分,术后为86分。术前平均对线为内翻5度,范围从外翻25度至内翻20度,术后平均对线为外翻4度,范围从中立位至外翻6度。除1例患者外,所有患者的疼痛和稳定性均有改善。15例同种异体骨均与宿主骨愈合,13例有融合迹象。同种异体骨无感染或骨折发生。发生了1例与同种异体骨直接相关的并发症;该患者术后3年,胫骨近端同种异体骨上方的胫骨假体发生骨折。还发生了另外3例并发症。1例接受股骨远端同种异体骨移植的患者出现胫骨假体松动,第2例接受股骨远端同种异体骨移植的患者发生胫骨近端骨折,第3例为术中髌腱撕脱。这些结果表明,结构性同种异体骨移植可为处理失败的全膝关节置换术中的大骨缺损提供一种满意的方法。

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