Biggs R
Br J Haematol. 1977 Apr;35(4):487-504. doi: 10.1111/j.1365-2141.1977.tb00615.x.
A study has been made by the Haemophilia Centre Directors of the United Kingdom and Northern Ireland. From 1969 to 1974 2600 patients with haemophilia A and 388 with haemophilia B attended Haemophilia Centres for treatment. Of these patients, 71 are known to have died in the survey period. A record is presented of the amounts and types of therapeutic materials used each year during this time. The incidenceof jaundice and anti-factor VIII and anti-factor IX antibodies was recorded.
英国和北爱尔兰血友病中心主任开展了一项研究。1969年至1974年期间,2600名甲型血友病患者和388名乙型血友病患者前往血友病中心接受治疗。在这些患者中,已知有71人在调查期间死亡。本文记录了这一时期每年使用的治疗材料的数量和类型。记录了黄疸以及抗凝血因子VIII和抗凝血因子IX抗体的发生率。