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大鼠肠道上皮细胞内的铁转运:生化与超微结构观察

Intracellular iron transport in rat intestinal epithelium: biochemical and ultrastructural observations.

作者信息

Humphrys J, Walpole B, Worwood M

出版信息

Br J Haematol. 1977 Jun;36(2):209-17. doi: 10.1111/j.1365-2141.1977.tb00641.x.

DOI:10.1111/j.1365-2141.1977.tb00641.x
PMID:871434
Abstract

Iron absorption by the rat intestinal epithelial cell has been studied by differential centrifugation of mucosal homogenates and by electron microscopic autoradiography. Autoradiography of both subcellular pellets and whole gut confirmed the biochemical findings. Mitochondria play a quantitatively significant role in iron metabolism within the epithelial cell but do not take part in the transport of iron across the cell during iron absorption.

摘要

通过对黏膜匀浆进行差速离心以及电子显微镜放射自显影术,对大鼠肠道上皮细胞的铁吸收进行了研究。亚细胞沉淀和整个肠道的放射自显影证实了生化研究结果。线粒体在上皮细胞内的铁代谢中起着数量上显著的作用,但在铁吸收过程中不参与铁跨细胞的转运。

相似文献

1
Intracellular iron transport in rat intestinal epithelium: biochemical and ultrastructural observations.大鼠肠道上皮细胞内的铁转运:生化与超微结构观察
Br J Haematol. 1977 Jun;36(2):209-17. doi: 10.1111/j.1365-2141.1977.tb00641.x.
2
The subcellular distribution of 59 Fe in small intestinal mucosa: studies with normal, iron deficient and iron overloaded rats.59铁在小肠黏膜中的亚细胞分布:对正常、缺铁和铁过载大鼠的研究
Br J Haematol. 1972 Mar;22(3):265-72. doi: 10.1111/j.1365-2141.1972.tb05672.x.
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Small intestinal regulation of iron absorption in the rat.
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Ultrastructural cytochemistry of iron absorption.铁吸收的超微结构细胞化学
Am J Pathol. 1978 Dec;93(3):707-27.
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[Electron microscopic study of 3H-leucine transport between the internal body environment and the enteral environment].[3H-亮氨酸在体内环境与肠内环境之间转运的电子显微镜研究]
Tsitologiia. 1983 Jul;25(7):748-53.
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Ultrastructural studies on iron absorption in normal mouse duodenum.正常小鼠十二指肠铁吸收的超微结构研究。
Nutr Rev. 1972 Sep;30(9):214-6. doi: 10.1111/j.1753-4887.1972.tb04047.x.
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[Iron absorption].[铁吸收]
Schweiz Med Wochenschr. 1971 Nov 6;101(44):1569-75.
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Kinetics of the subcellular distribution of iron and cobalt in the intestinal mucosa of the rat.大鼠肠黏膜中铁和钴的亚细胞分布动力学
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[The lipid metabolism of the small intestine and its correlation to the lipid and lipoprotein metabolism of the total organism].[小肠的脂质代谢及其与整个机体脂质和脂蛋白代谢的相关性]
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引用本文的文献

1
Ultrastructural cytochemistry of iron absorption.铁吸收的超微结构细胞化学
Am J Pathol. 1978 Dec;93(3):707-27.