Kozubski W, Prusiński A
Katedry i Kliniki Neurologii Akademii Medycznej w Lodzi.
Neurol Neurochir Pol. 1995 Nov-Dec;29(6):929-35.
The contemporary measures against migraine attacks are not fully satisfying, thus the migraine episode is still a challenge in treatment. In 1993 Hering and Steiner proposed valproic acid for the interruption of migraine attacks. The authors present the results of their own study comparing the effects of sodium valproate (SV) and ergotamine plus caffeine (Coffecorn) in this respect. 82 attacks in 20 patients were treated altogether. The effectiveness of SV was statistically not different from that of ergotamine--the drug recognized formerly as the first choice one in the abortion of migraine attacks.
目前针对偏头痛发作的治疗措施并不完全令人满意,因此偏头痛发作在治疗上仍然是一个挑战。1993年,赫林和施泰纳提出使用丙戊酸来终止偏头痛发作。作者展示了他们自己的研究结果,比较了丙戊酸钠(SV)和麦角胺加咖啡因(Coffecorn)在这方面的效果。共对20名患者的82次发作进行了治疗。SV的疗效在统计学上与麦角胺并无差异——麦角胺曾是偏头痛发作终止治疗中公认的首选药物。