Roberts G M, Roberts E E, Davies R L, Lawrie B W
Br J Radiol. 1977 Jun;50(594):415-8. doi: 10.1259/0007-1285-50-594-415.
Thrombus formation on the surface of a variety of arterial catheters and guidewires has been studies in dogs. Heparin-bonding of catheters and guidewires greatly reduced surface thrombus deposition even in the most thrombogenic material tested, and under the conditions of these experiements heparin-bonding was more effective than systemic heparinization.