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1
Erythema nodosum associated with pregnancy and oral contraceptives.与妊娠及口服避孕药相关的结节性红斑。
Br Med J. 1977 Jun 11;1(6075):1509-10. doi: 10.1136/bmj.1.6075.1509.
2
Erythema nodosum and oral contraceptives.结节性红斑与口服避孕药
Br Med J. 1977 Nov 19;2(6098):1353. doi: 10.1136/bmj.2.6098.1353-a.
3
The effect of pregnancy and two different contraceptive pills on serum lipids and lipoproteins in a woman with a type III hyperlipoproteinaemia pattern.妊娠及两种不同避孕药对一名Ⅲ型高脂蛋白血症模式女性血清脂质和脂蛋白的影响。
Br J Obstet Gynaecol. 1978 Feb;85(2):127-33. doi: 10.1111/j.1471-0528.1978.tb10466.x.
4
Control of fertility with oral medication.口服药物控制生育。
West J Surg Obstet Gynecol. 1964 Jul-Aug;72:222-9.
5
[Erythema nodosum and oral contraception. Demonstration of an anti-ethinyl estradiol antibody].[结节性红斑与口服避孕药。抗炔雌醇抗体的证实]
Nouv Presse Med. 1981 Feb 28;10(9):712.
6
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 40-1982. Tender hepatomegaly in a 29-year-old woman.马萨诸塞州总医院病例记录。每周临床病理讨论。病例40 - 1982。一名29岁女性的肝脏肿大伴压痛
N Engl J Med. 1982 Oct 7;307(15):934-42. doi: 10.1056/NEJM198210073071508.
7
Thyroid function tests under the effect of steroidal contraceptives compared to normal pregnancy.与正常妊娠相比，甾体避孕药作用下的甲状腺功能测试
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8
[Dermatological complications caused by oral contraceptives].[口服避孕药引起的皮肤并发症]
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Oral contraceptive-induced esophageal ulcer. Two cases and literature review.口服避孕药所致食管溃疡。两例报告并文献复习。
Dig Dis Sci. 1991 Oct;36(10):1489-90. doi: 10.1007/BF01296821.
10
Oral contraceptives and systemic lupus erythematosus.口服避孕药与系统性红斑狼疮
Arthritis Rheum. 1980 Dec;23(12):1396-8. doi: 10.1002/art.1780231213.

引用本文的文献

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A Case of Erythema Nodosum in a 20-Year-Old Female During the Postpartum Period.一名20岁产后女性的结节性红斑病例。
Cureus. 2024 Apr 18;16(4):e58526. doi: 10.7759/cureus.58526. eCollection 2024 Apr.
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Unilateral Erythema Nodosum following Norethindrone Acetate, Ethinyl Estradiol, and Ferrous Fumarate Combination Therapy.醋酸炔诺酮、炔雌醇和富马酸亚铁联合治疗后出现的单侧结节性红斑。
Case Rep Obstet Gynecol. 2016;2016:5726416. doi: 10.1155/2016/5726416. Epub 2016 Mar 27.
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Multiclinical experiences in erythema nodosum: rheumatology clinics versus dermatology and infection diseases clinics.结节性红斑的多临床经验：风湿科与皮肤科和感染科。
Rheumatol Int. 2013 Feb;33(2):315-8. doi: 10.1007/s00296-012-2413-5. Epub 2012 Mar 24.
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A Case of Assisted Reproductive Therapy-induced Erythema Nodosum.一例辅助生殖治疗诱发的结节性红斑病例。
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Erythema nodosum associated with streptococcal infection in pregnancy.妊娠期间与链球菌感染相关的结节性红斑
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6
Reactive arthritis.反应性关节炎
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本文引用的文献

1
Antinuclear antibodies, rheumatoid factor and C-reactive protein in serum of normal women using oral contraceptives.服用口服避孕药的正常女性血清中的抗核抗体、类风湿因子和C反应蛋白。
Arthritis Rheum. 1971 Mar-Apr;14(2):239-48. doi: 10.1002/art.1780140208.
2
[Effect of hormonal climate on the intensity of the Arthus type immunological reaction].[激素环境对阿瑟斯型免疫反应强度的影响]
C R Seances Soc Biol Fil. 1974;168(1):147-51.
3
Erythema nodosum and serological lupus erythematosus. Simultaneous occurrence in a patient using oral contraceptives.结节性红斑与血清学红斑狼疮。一名使用口服避孕药的患者中同时出现。
Arch Dermatol. 1973 Nov;108(5):716-8.
4
Depressed lymphocyte response to P.H.A. in women taking oral contraceptives.服用口服避孕药的女性对植物血凝素的淋巴细胞反应降低。
Lancet. 1972 May 27;1(7761):1185. doi: 10.1016/s0140-6736(72)91415-8.

与妊娠及口服避孕药相关的结节性红斑。

Erythema nodosum associated with pregnancy and oral contraceptives.

作者信息

Bombardieri S, Munno O D, Di Punzio C, Pasero G

出版信息

Br Med J. 1977 Jun 11;1(6075):1509-10. doi: 10.1136/bmj.1.6075.1509.

DOI:10.1136/bmj.1.6075.1509
PMID:871635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1607270/
Abstract

Erythema nodosum recurred in a woman during each of her four pregnancies and every time she was started on oral contraceptives. The lesions always disappeared in the fifth month of gestation or when contraceptives were withdrawn. Erythema nodosum is mediated by immune mechanisms, and both pregnancy and oral contraceptive use can interfere with the immune system. The concentrations of oestrogen and progesterone or the ratio between them may be critical to the development of erythema nodosum. The observation that the lesions spontaneously resolved in the fifth month of pregnancy supports this hypothesis.

摘要

一名女性在其四次怀孕的每一次期间以及每次开始服用口服避孕药时都会出现结节性红斑。病变总是在妊娠第五个月或停用避孕药时消失。结节性红斑由免疫机制介导，而怀孕和使用口服避孕药均可干扰免疫系统。雌激素和孕激素的浓度或它们之间的比例可能对结节性红斑的发生至关重要。病变在妊娠第五个月自发消退这一观察结果支持了这一假说。