Boccon-Gibod L
Clinique Urologique, Hôpital Bichat, Paris, France.
Eur Urol. 1996;29 Suppl 2:62-8. doi: 10.1159/000473842.
Localised prostate cancer (T1/T2) can be managed using a conservative (expectant) approach or by radical treatment with curative intent. Expectant management involves observation until symptoms of local/distant progression appear. Radical treatment with intent to cure is based on the destruction (radiation therapy or cryosurgery) or removal (surgery) of the tumour. Many options are offered to patients with T1/T2 prostate cancer. Expectant therapy may be considered in patients with limited life expectancy, curative treatment should be considered in the others, taking into account the high rate of cancer-related deaths after 10 years. Moreover, accurate staging should lead to a better selection of patients likely to be cured by monotherapy (surgery or radiation therapy depending on the patient's and doctor's biases). Surgery probably offers the advantage of the certainty of removal over the hypothetical destruction of the whole tumour provided by radiation therapy.
局限性前列腺癌（T1/T2）可采用保守（观察等待）方法或采用根治性治疗。观察等待管理包括观察，直至出现局部/远处进展的症状。根治性治疗旨在通过破坏（放射治疗或冷冻手术）或切除（手术）肿瘤。对于T1/T2前列腺癌患者有多种选择。预期寿命有限的患者可考虑观察等待治疗，其他患者应考虑根治性治疗，同时要考虑到10年后与癌症相关的高死亡率。此外，准确分期应有助于更好地选择可能通过单一疗法（手术或放射治疗，取决于患者和医生的偏好）治愈的患者。手术可能具有优势，即与放射治疗对整个肿瘤的假设性破坏相比，手术能确保切除肿瘤。
