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[作为突触超微结构调节剂的δ睡眠诱导肽]

[The delta sleep-inducing peptide as a modulator of synaptic ultrastructure].

作者信息

Mendzheritskiĭ A M, Mikhaleva I I, Matsionis A E, Pavilaĭtite P E

出版信息

Morfologiia. 1994 Apr-Jun;106(4-6):55-63.

PMID:8718636
Abstract

Results of morphometric study of ultrastructure of axosomatic and axospinous synapses of rat sensomotor neocortex after DSIP administration and in hypoxia showed that the peptide administration resulted in multidirectional changes in these type contacts in intact animals. This, apparently, is connected with their different functional specialization. Preliminary DSIP administration prevented changes, appearing in hypoxia in most of the parameters studied both in axosomatic and axospinous synapses.

摘要

给予DSIP后以及在缺氧状态下,对大鼠感觉运动新皮质轴体和轴棘突触超微结构进行形态计量学研究的结果表明,在完整动物中给予该肽导致这些类型突触出现多方向变化。显然,这与其不同的功能特化有关。预先给予DSIP可防止在缺氧状态下轴体和轴棘突触中所研究的大多数参数出现变化。

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