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[给予δ-睡眠诱导肽期间轴突-胞体突触激活的形态学证据]

[Morphometric evidence of activation of axo-somatic synapses during administration of delta sleep-inducing peptide].

作者信息

Mendzheritskiĭ A M, Kuraev G A, Mikhaleva I I, Povilaĭtite P E

出版信息

Biull Eksp Biol Med. 1992 Feb;113(2):202-3.

PMID:1611076
Abstract

Computed morphometry proved activation of neocortex layer III-V axosomatic synapses. This is evident from an increase in the mean plasmalemma length, that in the active synapse zones on neurone bodies and width of the synaptic cleft, this being induced by a single intraperitoneal administration of delta-sleep-inducing peptide. The activation of the axosomatic synapses correlates with elevated GABA levels in the cerebral hemispheres cortex.

摘要

计算机形态测量学证实了新皮层Ⅲ-Ⅴ层轴体突触的激活。单次腹腔注射δ-睡眠诱导肽后,神经元胞体上活跃突触区的平均质膜长度、突触间隙宽度增加,由此可见轴体突触被激活。轴体突触的激活与大脑半球皮质中γ-氨基丁酸(GABA)水平升高相关。

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