Macdonald R L
Section of Neurosurgery, University of Chicago Medical Center, Illinois 60637, USA.
J Neurosci Nurs. 1996 Apr;28(2):93-8. doi: 10.1097/01376517-199604000-00005.
Controversies surround the indications for and methods of diagnosis of carotid stenosis. Carotid endarterectomy is of proven value for patients presenting with transient ischemic attacks or minor stroke and angiographic atherosclerotic carotid stenosis of greater than 70% if endarterectomy can be carried out with a surgical morbidity and mortality of less than 6%. It is generally not indicated for stenosis less than 30%. For intermediate levels of stenosis, studies to determine its efficacy are ongoing. Endarterectomy can also decrease the risk of stroke in asymptomatic patients, although indications in asymptomatic patients remain controversial. Conventional angiography remains the gold standard for diagnosis of carotid stenosis. Improvements in ultrasound technology and magnetic resonance angiography have led some surgeons to rely only on these tests preoperatively rather than perform conventional angiography. It would be advantageous to be able to avoid the 1% risk of angiography but further study is indicated before this approach can be accepted. Carotid angioplasty remains an investigational procedure.
关于颈动脉狭窄的诊断指征和方法存在争议。对于出现短暂性脑缺血发作或轻度中风且血管造影显示动脉粥样硬化性颈动脉狭窄超过70%的患者,如果能在手术发病率和死亡率低于6%的情况下进行颈动脉内膜切除术,那么该手术已被证明具有价值。对于狭窄程度小于30%的情况,通常不建议进行该手术。对于中度狭窄水平,确定其疗效的研究正在进行中。颈动脉内膜切除术也可以降低无症状患者中风的风险,尽管无症状患者的手术指征仍存在争议。传统血管造影仍然是诊断颈动脉狭窄的金标准。超声技术和磁共振血管造影的改进使一些外科医生在术前仅依赖这些检查,而不进行传统血管造影。能够避免血管造影1%的风险将是有利的,但在这种方法被接受之前还需要进一步研究。颈动脉血管成形术仍然是一种研究性手术。