Kunesová M, Hainer V, Hergetová H, Zák A, Parízková J, Horejs J, Stich V
IVth Department of Internal Medicine, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.
Sb Lek. 1995;96(3):257-67.
Abdominal type of obesity is linked to risk factors of atherosclerosis and to metabolic diseases. 216 women, aged 17 to 67 years, mean age 43.1 +/- 0.76, mean weight 108.7 +/- 1.6 kg and mean BMI 39.57 kg/m2, were examined. Body composition was assessed by hydrodensitometry, fat distribution was determined by simple anthropometric measurements (waist circumference, sagittal abdominal diameter at the level L4,5, waist to hip ratio-WHR and waist to thigh ratio-WTR), by computed tomography estimating of visceral fat area and by the ultrasound assessment of visceral fat. Close correlation of visceral fat area determined by CT with the ultrasound assessment of visceral fat was found (r = 0.71). In contrast to WHR, a strong correlation of the waist circumference and sagittal abdominal diameter to total body fat content (r = 0.89, r = 0.84, respectively). Close relation of the waist circumference, sagittal abdominal diameter and WTR to visceral fat examined by ultrasound was discovered (r = 0.61, r = 0.66 and r = 0.58, respectively). The sample was divided into quintiles according to waist circumference, abdominal sagittal diameter and WHR. After adjustment for weight and age, waist circumference and sagittal abdominal diameter tend to be more closely related to the metabolic variables (total cholesterol, HDL-cholesterol, triglycerides, fasting blood glucose, fasting insulin, uric acid) and to the arterial blood pressure than WHR. In the group followed only weak relation was found between anthropometric measures of fat distribution and occurrence of diseases complicating obesity, probably as a result of a high overall fatness connected with a high content of visceral fat.
腹部肥胖类型与动脉粥样硬化的危险因素以及代谢性疾病相关。对216名年龄在17至67岁之间的女性进行了检查，平均年龄为43.1±0.76岁，平均体重为108.7±1.6千克，平均体重指数为39.57千克/平方米。通过水下密度测定法评估身体成分，通过简单的人体测量（腰围、L4,5水平的腹部矢状径、腰臀比-WHR和腰大腿比-WTR）、计算机断层扫描估计内脏脂肪面积以及超声评估内脏脂肪来确定脂肪分布。发现通过CT测定的内脏脂肪面积与超声评估的内脏脂肪之间具有密切相关性（r = 0.71）。与腰臀比不同，腰围和腹部矢状径与全身脂肪含量具有很强的相关性（分别为r = 0.89和r = 0.84）。发现腰围、腹部矢状径和腰大腿比与超声检查的内脏脂肪密切相关（分别为r = 0.61、r = 0.66和r = 0.58）。根据腰围、腹部矢状径和腰臀比将样本分为五等分。在对体重和年龄进行调整后，腰围和腹部矢状径与代谢变量（总胆固醇、高密度脂蛋白胆固醇、甘油三酯、空腹血糖、空腹胰岛素、尿酸）以及动脉血压之间的关系往往比腰臀比更为密切。在随访组中，发现脂肪分布的人体测量指标与肥胖并发症的发生之间只有微弱的关系，这可能是由于总体脂肪含量高且内脏脂肪含量高所致。
