Stringer S P
Department of Otolaryngology, University of Florida, College of Medicine, Gainesville, Florida, USA.
Oncology (Williston Park). 1995 Jun;9(6):547-54; discussion 554, 557-8.
The surgical management of neck metastases from head and neck cancer consists primarily of neck dissection. An awareness of both the cervical anatomy and natural history of squamous cell carcinoma of the upper aerodigestive tract is necessary to understand the role of neck dissection and to appreciate when it may be appropriate to modify the standard radical neck dissection. The use of imaging to augment palpation of the neck has resulted in greater accuracy in identifying neck metastases and has further clarified the role of modified neck dissections. Depending on the site and size of the primary tumor, radiation therapy, modified neck dissection, or selective neck dissection are all appropriate options for the elective treatment of the neck when there is a high risk of occult metastasis. Therapeutic neck dissection alone is adequate for early-stage neck disease, but must be combined with irradiation for more advanced stages. Regional control of tumor metastases is highly dependent on the stage of neck disease and the presence of extranodal cancer spread.
头颈部癌颈部转移灶的外科治疗主要包括颈部清扫术。了解颈部解剖结构以及上呼吸道消化道鳞状细胞癌的自然病程,对于理解颈部清扫术的作用以及认识何时适合对标准根治性颈部清扫术进行改良十分必要。利用影像学手段辅助颈部触诊,提高了识别颈部转移灶的准确性,并进一步明确了改良颈部清扫术的作用。根据原发肿瘤的部位和大小,对于存在隐匿转移高风险的患者,放射治疗、改良颈部清扫术或选择性颈部清扫术都是选择性治疗颈部的合适选择。单纯治疗性颈部清扫术适用于早期颈部疾病,但对于更晚期的病例必须联合放疗。肿瘤转移灶的区域控制高度依赖于颈部疾病的分期以及有无结外癌扩散。