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冠状动脉空气栓塞:发病率、严重程度及建议的治疗方法。

Coronary air embolism: incidence, severity, and suggested approaches to treatment.

作者信息

Khan M, Schmidt D H, Bajwa T, Shalev Y

机构信息

Department of Medicine, University of Wisconsin Medical School-Milwaukee Clinical Campus, Sinai Samaritan Medical Center, USA.

出版信息

Cathet Cardiovasc Diagn. 1995 Dec;36(4):313-8. doi: 10.1002/ccd.1810360406.

Abstract

Because no well-controlled study of inadvertent coronary air embolism has been done to truly quantify the incidence of this cardiac catheterization complication, we wanted to determine its incidence and severity in an active teaching medical center and assess approaches to treatment. We retrospectively reviewed 3,715 coronary angiogram and PTCA reports performed over 32 months. Further, we classified severity based on angiographic findings and symptoms as minimal, mild, moderate, and massive. Two independent angiographers reviewed 764 consecutive cines performed in the first 2 months of training of each new fellow and 740 cines performed in the last 2 months of training. We found that during the first 2 months of training the overall incidence for significant intracoronary air embolism was 0.19% (7 documented cases) compared with 0.2% (3 cases) for non-reported, minimal asymptomatic air embolism. The estimated incidence for total air emboli events was 0.27% (10/3,715). We did not find coronary air emboli in the 740 cines performed at the end of fellowship training. Additionally, the incidence of coronary air emboli during PTCA training was much higher compared with coronary angiography training (0.84 vs. 0.24%). Although there is no best technique to restore blood flow after blockage by air emboli, we suggest as options aspirating the air or forcefully injecting saline, with auxiliary supportive measures like 100% oxygen, IABP, CPR, and DC cardioversion.

摘要

由于尚未进行关于意外冠状动脉空气栓塞的严格对照研究以真正量化这种心脏导管插入术并发症的发生率,我们希望确定其在一家活跃的教学医学中心的发生率和严重程度,并评估治疗方法。我们回顾性分析了32个月内进行的3715份冠状动脉造影和经皮冠状动脉腔内血管成形术(PTCA)报告。此外,我们根据血管造影结果和症状将严重程度分为轻微、轻度、中度和重度。两名独立的血管造影师审查了每位新学员培训前两个月连续进行的764份电影造影以及培训最后两个月进行的740份电影造影。我们发现,在培训的前两个月,严重冠状动脉内空气栓塞的总体发生率为0.19%(记录在案的7例),相比之下,未报告的轻微无症状空气栓塞发生率为0.2%(3例)。估计总的空气栓塞事件发生率为0.27%(10/3715)。在学员培训结束时进行的740份电影造影中未发现冠状动脉空气栓塞。此外,PTCA培训期间冠状动脉空气栓塞的发生率远高于冠状动脉造影培训期间(0.84%对0.24%)。尽管在空气栓塞阻塞后恢复血流没有最佳技术,但我们建议可选择抽吸空气或强力注射生理盐水,并辅以100%氧气、主动脉内球囊反搏(IABP)、心肺复苏(CPR)和直流电复律等支持措施。

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