Rowe J G, Byrne J V, Molyneux A, Rajagopalan B
MRC Magnetic Resonance Spectroscopy Unit, John Radcliffe Hospital, Headington, Oxford, UK.
Br J Neurosurg. 1995;9(6):749-57. doi: 10.1080/02688699550040710.
Twenty patients with aneurysms were studied with transcranial Doppler before, during and after endovascular treatment with Guglielmi detachable coils. Catheterization of the anterior circulation decreased middle cerebral artery velocities by 15-20%. Inserting coils into the aneurysms increased pulsatility indices modestly, reflecting a stiffening of the cerebral circulation. Pre- and posttreatment velocities were not significantly different, and there was no evidence of coil embolization precipitating vasospasm. The haemodynamic stability, seen during and after therapy, suggests that coil embolization may prove a safe alternative way of treating acutely ruptured aneurysms.
对20例患有动脉瘤的患者在使用 Guglielmi 可脱性弹簧圈进行血管内治疗前、治疗期间及治疗后进行了经颅多普勒研究。前循环导管插入术使大脑中动脉流速降低了15% - 20%。将弹簧圈插入动脉瘤使搏动指数略有增加，这反映了脑循环的僵硬。治疗前和治疗后的流速没有显著差异，也没有证据表明弹簧圈栓塞会引发血管痉挛。治疗期间及治疗后观察到的血流动力学稳定性表明，弹簧圈栓塞可能是治疗急性破裂动脉瘤的一种安全的替代方法。
