Gandhi M K, Chandler J E
Department of Haematology, Middlesbrough General Hospital, South Tees Acute Hospitals Trust, UK.
Clin Lab Haematol. 1995 Sep;17(3):247-50.
Hypersomnolence syndrome has been well described in patients with acute lymphoblastic leukaemia (ALL) following cranial irradiation. It is most frequently seen in children. In adults it is clinically very mild. We describe a case of a particularly severe and prolonged post radiation hypersomnolence syndrome in an adult with ALL. The hypersomnolence syndrome is discussed in the context of side effects of central nervous system directed therapy in elderly patients with ALL.
嗜睡综合征在接受颅脑照射后的急性淋巴细胞白血病（ALL）患者中已有详细描述。它最常见于儿童。在成人中，其临床表现非常轻微。我们描述了一例成年ALL患者出现的特别严重且持续时间长的放疗后嗜睡综合征。本文在老年ALL患者中枢神经系统定向治疗的副作用背景下对嗜睡综合征进行了讨论。
