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喂食镁缺乏及铈掺杂饮食的大鼠组织中的铈含量。

Levels of cerium in the tissues of rats fed a magnesium-restricted and cerium-adulterated diet.

作者信息

Eapen J T, Kartha C C, Rathinam K, Valiathan M S

机构信息

Division of Cellular and Molecular Cardiology and Division of Materials Toxicology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

出版信息

Bull Environ Contam Toxicol. 1996 Feb;56(2):178-82. doi: 10.1007/s001289900027.

DOI:10.1007/s001289900027
PMID:8720088
Abstract

Cerium, a lanthanide, is the most abundant rare earth element present in monazite and is biologically active. It has been postulated that cerium toxicity in conjunction with magnesium deficiency causes tropical endomyocardial fibrosis, a restrictive human cardiomyopathy (Valiathan et al. 1989; Valiathan and Kartha 1990). Generally, lanthanides are known to be poorly absorbed (Durbin et al. 1956; Evans 1990). The present study was carried out to ascertain whether magnesium deficiency promotes accumulation of cerium in various organs of rats.

摘要

铈是一种镧系元素,是独居石中含量最丰富的稀土元素,且具有生物活性。据推测,铈的毒性与镁缺乏共同作用会导致热带心内膜心肌纤维化,这是一种限制性人类心肌病(瓦利亚坦等人,1989年;瓦利亚坦和卡尔塔,1990年)。一般来说,已知镧系元素的吸收率很低(德宾等人,1956年;埃文斯,1990年)。本研究旨在确定镁缺乏是否会促进铈在大鼠各器官中的蓄积。

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