Kurokawa S, Tokura Y, Nham N X, Sudoh H, Wakita H, Furukawa F, Takigawa M
Department of Dermatology, Hamamatsu University School of Medicine, Japan.
J Dermatol. 1996 Jan;23(1):37-41. doi: 10.1111/j.1346-8138.1996.tb03965.x.
A 30-year-old Japanese man presented with an erythematous, papulonodular eruption on his face and upper trunk, which rapidly progressed into severely exuberant, ulcerative lesions with a confluent tendency. His other symptoms included a high fever and general malaise. Complete blood cell counts showed neutrophilia with increased percentages of myelocytes and metayelocytes. The systemic administration of corticosteroids improved his skin lesions, leaving scars and milia. During tapering of corticosteroids, however, the patient developed posterior scleritis of his eyes and pyoderma gangrenosum-like eruptions on the lower legs. Our patient's history suggests that pyoderma gangrenosum-like eruptions and posterior scleritis are disorders associated with acne fulminans.
一名30岁的日本男性,面部和上躯干出现红斑性丘疹结节性皮疹,迅速发展为严重的、增生性溃疡性病变且有融合倾向。他的其他症状包括高热和全身不适。全血细胞计数显示中性粒细胞增多,髓细胞和晚幼粒细胞百分比增加。全身应用皮质类固醇改善了他的皮肤病变,但留下了疤痕和粟丘疹。然而,在逐渐减少皮质类固醇用量期间,患者出现了眼部后巩膜炎和小腿部坏疽性脓皮病样皮疹。我们患者的病史提示,坏疽性脓皮病样皮疹和后巩膜炎是与暴发性痤疮相关的疾病。