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厌氧棒状杆菌对小鼠黑色素瘤的比较作用

Comparative effect of anaerobic coryneforms on a murine melanoma.

作者信息

Paslin D A

出版信息

Cancer. 1977 Jun;39(6):2405-10. doi: 10.1002/1097-0142(197706)39:6<2405::aid-cncr2820390615>3.0.co;2-w.

Abstract

Ten strains of anaerobic Corynebacteria were compared in their effect on survival of C57BL/6 mice, bearing subcutaneously inoculated B16 melanomas. The corynebacterial suspensions were injected intralesionally twice weekly for five injections. Significant permanent tumor regression was not obtained. Significant prolongation of survival was observed in mice treated with seven of the corynebacterial strains.

摘要

对10株厌氧棒状杆菌进行了比较,观察它们对皮下接种B16黑色素瘤的C57BL/6小鼠存活情况的影响。将棒状杆菌悬液每周两次瘤内注射,共注射五次。未观察到明显的永久性肿瘤消退。在用7株棒状杆菌菌株处理的小鼠中观察到存活时间显著延长。

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