Sarrat R, Whyte J, Torres A, Lostalé F, Díaz M P
Department of Morphology, School of Medicine, University of Zaragoza, Spain.
Histol Histopathol. 1996 Jan;11(1):1-6.
We have performed an experimental study on rats and dogs to evaluate the long term effects (from 1 to 12 months) of vasectomy on the structure of the testis. From four months after vasectomy onwards, the specimens showed very important changes in the seminiferous epithelium and Sertoli cells, with an obvious thickening of the basement membrane that supports the epithelium. The deterioration depended on the time passed and, over six months after vasectomy, the alterations were very clear and the seminiferous tubules became atrophic and shrunk, sometimes without any remains of seminiferous epithelium and with an important hypertrophy of the interlobular interstitial tissue, although we did not see an increase in the number of Leydig cells. Alterations due to vasectomy depend on the animal species, the peculiarities of techniques and, of course, the time passed after surgery.
我们对大鼠和狗进行了一项实验研究，以评估输精管结扎术对睾丸结构的长期影响（1至12个月）。输精管结扎术后四个月起，标本显示生精上皮和支持细胞有非常重要的变化，支持上皮的基底膜明显增厚。这种退化取决于术后经过的时间，输精管结扎术后六个月以上，变化非常明显，生精小管萎缩并缩小，有时没有任何生精上皮残留，小叶间间质组织有明显肥大，尽管我们没有看到睾丸间质细胞数量增加。输精管结扎术引起的变化取决于动物种类、技术特点，当然还有术后经过的时间。
