Neumann B, Barlow D P
Institute of Molecular Pathology, Vienna, Austria.
Curr Opin Genet Dev. 1996 Apr;6(2):159-63. doi: 10.1016/s0959-437x(96)80045-1.
Allele-specific DNA methylation has been observed for all tested imprinted genes and has a clear role in the imprinting mechanism. It remains to be resolved whether this role is to act as the gametic imprinting signal or to cause or maintain allele-specific expression.
在所有检测的印记基因中均观察到等位基因特异性DNA甲基化，且其在印记机制中具有明确作用。该作用是作为配子印记信号，还是导致或维持等位基因特异性表达，仍有待解决。
