Koszewska I
Z II Kliniki Psychiatrycznej IPiN w Warszawie.
Psychiatr Pol. 1996 Jan-Feb;30(1):113-25.
Frequency of occurrence of mania directly after depression during antidepressant treatment with drugs of different pharmacological characteristics was examined. 210 depressive episodes (in 118 patients) finished with switching from depression to mania were analyzed. It was found that this phenomenon occurs more frequently during therapy with classical tricyclic drugs (amitryptyline, imipramine) than with the second generation antidepressant drugs. A group of patients in whom the switch from depression to mania occurs independently of the kind of applied therapy, was observed.
研究了在使用不同药理特性药物进行抗抑郁治疗期间，抑郁症后直接出现躁狂症的发生频率。分析了210例（118名患者）以从抑郁转为躁狂结束的抑郁发作。发现这种现象在使用经典三环类药物（阿米替林、丙咪嗪）治疗期间比使用第二代抗抑郁药物时更频繁地出现。观察到一组患者，其从抑郁转为躁狂的情况与所应用治疗的类型无关。
