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肌肉注射育亨宾对白尾鹿中赛拉嗪的拮抗作用。

Antagonism of xylazine in white-tailed deer with intramuscular injection of yohimbine.

作者信息

Wallingford B D, Lancia R A, Soutiere E C

机构信息

Department of Forestry, North Carolina State University, Raleigh 27695, USA.

出版信息

J Wildl Dis. 1996 Apr;32(2):399-402. doi: 10.7589/0090-3558-32.2.399.

DOI:10.7589/0090-3558-32.2.399
PMID:8722289
Abstract

Eighteen free-ranging white-tailed deer (Odocoileus virginianus) were captured near Chestertown, Maryland (USA) from 15 February to 21 March, and 7 October to 13 November 1986. Deer were immobilized by intramuscular injection of 1.1 to 2.2 mg/kg xylazine hydrochloride and 1.8 to 4.4 mg/kg ketamine hydrochloride. Four captive deer from The Pennsylvania State University, Pennsylvania (USA), were immobilized on 16 September 1986 with 1.5 to 2.0 mg/kg xylazine hydrochloride. Intramuscular injection of yohimbine hydrochloride (0.4 mg/kg) was used to antagonize the immobilizations. Free-ranging adult ( > or = 17 months) males could stand after a mean (+/-SE) time of 7.3 +/- 2.4 min, adult females after 8.6 +/- 1.7 min, male fawns after 5.7 +/- 3.3 min, and female fawns after 8.9 +/- 1.9 min. Captive adult males could stand after 20.2 +/- 3.4 min. Intramuscular injections of yohimbine hydrochloride effectively and safely antagonized the xylazine hydrochloride in immobilized deer and were easier to administer than intravenous injections.

摘要

1986年2月15日至3月21日以及10月7日至11月13日期间,在美国马里兰州切斯特敦附近捕获了18只自由放养的白尾鹿(弗吉尼亚鹿)。通过肌肉注射1.1至2.2毫克/千克盐酸赛拉嗪和1.8至4.4毫克/千克盐酸氯胺酮使鹿麻醉。1986年9月16日,对来自美国宾夕法尼亚州宾夕法尼亚州立大学的4只圈养鹿,使用1.5至2.0毫克/千克盐酸赛拉嗪进行麻醉。肌肉注射盐酸育亨宾(0.4毫克/千克)用于对抗麻醉作用。自由放养的成年(≥17个月)雄性鹿在平均(±标准误)7.3±2.4分钟后能够站立,成年雌性鹿在8.6±1.7分钟后能够站立,雄性幼鹿在5.7±3.3分钟后能够站立,雌性幼鹿在8.9±1.9分钟后能够站立。圈养成年雄性鹿在20.2±3.4分钟后能够站立。肌肉注射盐酸育亨宾能有效且安全地对抗麻醉鹿体内的盐酸赛拉嗪,并且比静脉注射更容易给药。

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