戊巴比妥中毒的血液透析滤过治疗

Hemodiafiltration in pentobarbital poisoning.

作者信息

Bironneau E, Garrec F, Kergueris M F, Testa A, Nicolas F

机构信息

Department of Intensive Care Medicine, Toxicology, and Nephrology, Hôtel-Dieu Hospital, Nantes, France.

出版信息

Ren Fail. 1996 Mar;18(2):299-303. doi: 10.3109/08860229609052800.

DOI:10.3109/08860229609052800

PMID:8723368

Abstract

We report the use of continuous venovenous hemodiafiltration (CVVHD) in a case of massive intentional ingestion of pentobarbital associated with severe coma and hypotension. Despite a poor hemodynamic state, toxic epuration (15% of drug ingested) was obtained. However, death occurred 7 hr after the end of treatment. This report suggests that CVVHD can be effective in the treatment of massive pentobarbital intoxication.

摘要

我们报告了在一例因故意大量摄入戊巴比妥而导致严重昏迷和低血压的病例中使用持续静静脉血液透析滤过（CVVHD）的情况。尽管血流动力学状态不佳，但仍实现了毒物清除（摄入药物的15%）。然而，在治疗结束7小时后患者死亡。本报告表明，CVVHD在治疗大量戊巴比妥中毒方面可能有效。