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[西伯利亚原住民的线粒体DNA变异与美洲印第安人进化史的重建。限制性片段长度多态性]

[Mitochondrial DNA variation in native inhabitants of Siberia with reconstructions of the evolutional history of the American Indians. Restriction polymorphism].

作者信息

Sukernik R I, Shur T G, Starikovskaia E B, Uolles D K

机构信息

Emory University School of Medicine, Atlanta, Georgia 30322, USA.

出版信息

Genetika. 1996 Mar;32(3):432-9.

PMID:8723636
Abstract

Restriction polymorphism of mitochondrial DNA (mtDNA) isolated from the blood of 107 Koryaks, 28 Northern Altaians, and 23 Kets was studied. The results were compared with similar data that in aggregate characterized haplotypes of 569 individual DNAs from 13 Siberian populations, in order to elucidate the genetic similarity and differences between mtDNA haplogroups of native Siberians and Americans. Natives of Siberia are distinguished by the significant variation of the composition and frequency of three (A, C, and D) of four haplogroups characteristic of American Indians. In the full composition, all four haplogroups-A, B, C, and D-are found only in a sample of Northern Altaians. The peculiarities of their geographical distribution in Asia allow us to consider the southern regions of Siberia and the adjacent territories of Central and East Asia as the site inhabited by the ancestors of the first wave of migrants to North America.

摘要

对从107名科里亚克人、28名北阿尔泰人以及23名凯特人的血液中分离出的线粒体DNA(mtDNA)的限制性多态性进行了研究。将结果与来自13个西伯利亚人群的569个个体DNA单倍型的综合特征的类似数据进行了比较,以阐明西伯利亚原住民和美洲人线粒体DNA单倍群之间的遗传相似性和差异。西伯利亚原住民的特点是美洲印第安人特有的四个单倍群中的三个(A、C和D)的组成和频率有显著变化。在完整的组成中,所有四个单倍群——A、B、C和D——仅在北阿尔泰人的样本中发现。它们在亚洲的地理分布特点使我们能够将西伯利亚南部地区以及中亚和东亚的相邻地区视为第一批移民到北美祖先居住的地方。

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Genetika. 1996 Mar;32(3):432-9.
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引用本文的文献

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Mitochondrial DNA and Y chromosome variation provides evidence for a recent common ancestry between Native Americans and Indigenous Altaians.线粒体 DNA 和 Y 染色体的变异为美洲原住民和阿尔泰原住民之间的最近共同祖先提供了证据。
Am J Hum Genet. 2012 Feb 10;90(2):229-46. doi: 10.1016/j.ajhg.2011.12.014. Epub 2012 Jan 25.
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Phylogeographic analysis of mitochondrial DNA in northern Asian populations.亚洲北部人群线粒体DNA的系统地理学分析
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Contrasting patterns of Y-chromosome variation in South Siberian populations from Baikal and Altai-Sayan regions.
贝加尔湖和阿尔泰山-萨彦岭地区南西伯利亚人群Y染色体变异的对比模式。
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Mitochondrial DNA diversity in indigenous populations of the southern extent of Siberia, and the origins of Native American haplogroups.西伯利亚南部土著人群的线粒体DNA多样性及美洲原住民单倍群的起源
Ann Hum Genet. 2005 Jan;69(Pt 1):67-89. doi: 10.1046/j.1529-8817.2003.00127.x.
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The dual origin and Siberian affinities of Native American Y chromosomes.美洲原住民Y染色体的双重起源及与西伯利亚的关联
Am J Hum Genet. 2002 Jan;70(1):192-206. doi: 10.1086/338457. Epub 2001 Nov 30.