Pearl S J, Lue F, MacLean A W, Heslegrave R J, Reynolds W J, Moldofsky H
University of Toronto Center for Sleep and Chronobiology, Toronto Hospital, Western Division, ON, Canada.
J Rheumatol. 1996 May;23(5):896-902.
To investigate the effects of bright light treatment on the symptoms of pain, mood, and sleep in patients with fibromyalgia (FM) reporting seasonality of symptoms on the Seasonal Pattern Assessment Questionnaire (SPAQ).
A randomized 10 week crossover study compared the effects of 4 weeks of "visible electromagnetic fields" (EMF) (light condition; mean 4750 lux, SD 2337 lux) to 4 weeks of "nonvisible EMF" (no light condition) in 14 patients with FM having a minimum SPAQ score of 11. The light visor system (Bio-Brite) was fitted with an opaque filter for the "nonvisible EMF" control condition.
No significant differences were found between treatment conditions on tenderness measured with dolorimetry, self-ratings of sleep, pain, mood, and global measures. Mood was not related to pain or sleep. There was significant reduction in depression scores and subjective pain, but increased tenderness and nocturnal awakenings related to time.
The were no significant differences between the light and no light conditions on pain, mood, or sleep in patients with FM reporting seasonality of symptoms. No relationship was found between mood and the symptoms of FM (i.e., pain, sleep, and fatigue).
在季节性模式评估问卷（SPAQ）中报告症状具有季节性的纤维肌痛（FM）患者中，研究强光治疗对疼痛、情绪和睡眠症状的影响。
一项随机的10周交叉研究，比较了14名SPAQ最低得分为11分的FM患者中，4周“可见电磁场”（EMF）（光照条件；平均4750勒克斯，标准差2337勒克斯）与4周“不可见EMF”（无光照条件）的效果。在“不可见EMF”对照条件下，光眼罩系统（Bio-Brite）安装了不透明滤光片。
在使用痛觉计测量的压痛、睡眠、疼痛、情绪的自我评分以及整体测量方面，各治疗条件之间未发现显著差异。情绪与疼痛或睡眠无关。抑郁评分和主观疼痛显著降低，但压痛和夜间觉醒次数随时间增加。
在报告症状具有季节性的FM患者中，光照条件和无光照条件在疼痛、情绪或睡眠方面无显著差异。未发现情绪与FM症状（即疼痛、睡眠和疲劳）之间存在关联。
