Little W C, Applegate R J
Department of Internal Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
Cardiol Clin. 1996 May;14(2):221-8. doi: 10.1016/s0733-8651(05)70275-7.
Angiographically apparent coronary artery stenoses limit coronary flow, produce symptomatic ischemia, and can be targeted for revascularization. Severe stenoses are more likely to occlude than segments without significant stenoses. Coronary angiography underestimates the extent of coronary atherosclerosis. Arterial segments without severe stenoses are much more common, and their risk of occlusion is not zero. Thus, the majority of myocardial infarctions are due to occlusion of arteries that do not contain obstructive coronary stenoses. Consequently, coronary angiography is not able to accurately predict the site of a coronary artery occlusion that subsequently will produce myocardial infarction.
血管造影显示的冠状动脉狭窄会限制冠状动脉血流，引发有症状的心肌缺血，并且可作为血管重建的目标。严重狭窄比无明显狭窄的节段更易发生闭塞。冠状动脉造影会低估冠状动脉粥样硬化的程度。无严重狭窄的动脉节段更为常见，其闭塞风险并非为零。因此，大多数心肌梗死是由不包含阻塞性冠状动脉狭窄的动脉闭塞所致。所以，冠状动脉造影无法准确预测随后会导致心肌梗死的冠状动脉闭塞部位。
