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眼科医生在沙眼衣原体感染中的作用。

The ophthalmologist's role in Chlamydia trachomatis infection.

作者信息

Mancino R, Valli E, Cedrone C, Nucci C, D'Ambrosi E, Cerulli L

机构信息

Dipartimento di Chirugia, Università Tor Vergata di Roma, Italia.

出版信息

Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 1994;71:79-83.

PMID:8724804
Abstract

Chlamydia Trachomatis (C.T.) most commonly causes cervicitis in women, often without overt symptoms; when untreated, it produces a clinically inapparent but persistent mild infection or an evident salpingitis. Either processes may lead to scarring of the falloppian tubes and fertility problems. A group of 30 women 20-35 years aged has undergone an ophthalmological routine examination; 7 of them presented a chronical follicular conjunctivitis and history of yellow-white cervical discharge, while the remaining 23 had a mild chronical follicular conjunctivitis but not genital symptoms. Each patient has undergone an immunofluorescent test with monoclonal antibody specific for C.T. on the samples collected by genital and conjunctival scraping and cytological evaluation of the above samples with Giemsa staining. 6 out of 7 patients with genital discharge were positive for C.T., one of which even for eye samples too; all eyes samples showed lymphomonocytes and neutrofilic cells in their eye samples. An additional 3 cases negative for C.T. showed this kind of cells in the eye scraping. The preliminary results of this study on mild follicular chronical conjunctivitis suggest that the Ophthalmologist could play an important role in order to make an early diagnosis in genital and eye infection by Chlamydial Trachomatis.

摘要

沙眼衣原体(C.T.)最常引起女性宫颈炎,通常无明显症状;若不治疗,会导致临床上不明显但持续的轻度感染或明显的输卵管炎。这两种情况都可能导致输卵管瘢痕形成和生育问题。一组30名年龄在20至35岁的女性接受了眼科常规检查;其中7人患有慢性滤泡性结膜炎且有黄白色宫颈分泌物病史,其余23人患有轻度慢性滤泡性结膜炎但无生殖器症状。每位患者都对通过生殖器和结膜刮片采集的样本进行了针对C.T.的单克隆抗体免疫荧光检测,并对上述样本进行吉姆萨染色的细胞学评估。7名有生殖器分泌物的患者中有6名C.T.呈阳性,其中1名眼部样本也呈阳性;所有眼部样本在其眼样本中均显示有淋巴细胞和中性粒细胞。另外3例C.T.阴性的病例在眼部刮片中也显示有这种细胞。这项关于轻度滤泡性慢性结膜炎的研究初步结果表明,眼科医生在沙眼衣原体生殖器和眼部感染的早期诊断中可能发挥重要作用。

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