Nonomura A, Mizukami Y, Kadoya M, Hasegawa T, Koshida K, Ohkawa M
Pathology Section, Kanazawa University Hospital, School of Medicine, Kanazawa University, Japan.
Radiat Med. 1996 Jan-Feb;14(1):37-42.
We report a case of adrenal myelolipoma found incidentally during abdominal ultrasound (US) and computed tomography (CT) examinations for hypertension. The patient was a 34-year-old woman with a history of hypertension. In June 1992, she complained of dizziness and easy fatigability and went to a hospital, where she was diagnosed as very hypertensive. She was hospitalized for further examinations. Abdominal US and CT incidentally revealed a right adrenal tumor. The tumor was visualized as a hyperechoic mass on US and an inhomogeneous low density mass with inner fat density and focal calcification on CT. Magnetic resonance (MR) imaging visualized the tumor as a high signal intensity mass on both T1- and T2-weighted images. Since the tumor was relatively large and the possibility of malignancy could not be completely excluded, resection of the tumor was performed. The resected tumor, which measured 5.2 x 3.8 x 2.5 cm, was located in the right adrenal medulla and was composed of mature fat cells and bone marrow elements, with all the developmental stages of hematopoietic cells. Small areas of fresh hemorrhage and calcification were found. The fat cell component showed focal myxoid change, but there were no immature or atypical cells. These features were consistent with myelolipoma. The clinical and pathologic features of adrenal myelolipoma are discussed.
我们报告一例肾上腺髓质脂肪瘤,该瘤是在因高血压进行腹部超声(US)和计算机断层扫描(CT)检查时偶然发现的。患者为一名34岁有高血压病史的女性。1992年6月,她主诉头晕和易疲劳,前往医院就诊,被诊断为高血压非常严重。她住院接受进一步检查。腹部超声和CT偶然发现右肾上腺有一个肿瘤。该肿瘤在超声上表现为高回声团块,在CT上表现为不均匀低密度团块,内部有脂肪密度和局灶性钙化。磁共振(MR)成像显示该肿瘤在T1加权像和T2加权像上均为高信号强度团块。由于肿瘤相对较大且不能完全排除恶性的可能性,遂对肿瘤进行了切除。切除的肿瘤大小为5.2×3.8×2.5 cm,位于右肾上腺髓质,由成熟脂肪细胞和骨髓成分组成,包含造血细胞的所有发育阶段。发现有小面积新鲜出血和钙化。脂肪细胞成分显示局灶性黏液样改变,但无不成熟或非典型细胞。这些特征符合髓质脂肪瘤。本文讨论了肾上腺髓质脂肪瘤的临床和病理特征。