Propoxyphene-associated deaths: methods, post-mortem levels in blood and liver.
作者信息
Rejent T A, Michalek R W, Lehotay J M
出版信息
Clin Toxicol. 1977;11(1):43-51. doi: 10.3109/15563657708989818.
PMID:872540
Abstract
Gas chromatographic methodology for the determination of d-propoxyphene in blood and liver samples is given. The method results in a clean extract and sharp response peaks. Quantitation is based on peak height ratios of propoxyphene and pyrroliphene. Post-mortem levels in blood range from 0.1-0.7 mg/dl; in liver from 1.1-18.9 mg/100 gm. The highest blood level has the lowest blood-liver ratio, the rest being widely variable. The incidence of propoxyphene in accidental and suicidal deaths appears to be increasing steadily.
摘要
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